Which situation necessitates enucleation in patients with retinoblastoma?

Enucleation, the surgical removal of the eye, may be required in cases where severe retinal detachment prevents vision. In retinoblastoma, if the tumor grows and leads to a complete detachment of the retina, it can result in irreversible vision loss. When the structural integrity of the eye is compromised to such an extent that vision cannot be restored, enucleation is often deemed necessary to manage the condition and prevent further complications, such as the risk of tumor spread.

In patients with retinoblastoma, the focus is on preserving as much vision as possible while also ensuring the effectiveness of treatment against the cancer. Therefore, situations that suggest irreversible damage, like severe retinal detachment, make enucleation a critical intervention. This allows for the prevention of further health issues and ensures that the tumor can be effectively managed.