Which rare manifestation may occur in retinoblastoma?

In retinoblastoma, pseudouveitis can occur as a rare manifestation due to several factors related to the tumor's involvement and the body's reaction to it. This condition can present as inflammation of the uveal tract, which may mimic true uveitis but is actually a result of the tumor's presence and associated retinal effects rather than an inflammatory disease process. The growth of the tumor can irritate the eye and create symptoms similar to uveitis, including redness, light sensitivity, and pain.

Understanding pseudouveitis in the context of retinoblastoma requires knowledge of the pathological mechanisms at play, such as the tumor's proximity to the uveal structures and the potential for secondary inflammation. This manifestation may not be as commonly recognized as others, making it a notable and rare complication linked to retinoblastoma.

Other options, like retinal hemorrhage and severe macular degeneration, are more common complications or complications associated with other ocular diseases or conditions, while chronic uveitis typically represents a systemic or infectious inflammatory process that is not directly tied to retinoblastoma specifically.