Which of the following is a known risk factor for age-related macular degeneration (AMD)?

A family history of macular degeneration is indeed a known risk factor for age-related macular degeneration (AMD). Research indicates that genetics play a significant role in the development of this condition. Individuals with a family history of AMD are at a greater risk because genetic predispositions can influence the structure and function of retinal cells, making them more susceptible to damage over time.

Moreover, AMD's mechanisms involve a combination of both environmental and genetic factors, but having relatives who have experienced AMD indicates a potential hereditary link that may increase an individual's likelihood of developing the disease.

Other options such as high blood pressure and increased screen time are associated with various eye health issues but are not direct risk factors specifically established for AMD. While frequent eye exams are a proactive measure for detecting eye problems early, they do not influence the risk of developing AMD directly.