Which condition is commonly associated with hyphema in patients?

Hyphema, which refers to the presence of blood in the anterior chamber of the eye, is commonly associated with sickle cell anemia. Patients with this genetic disorder can experience various ocular complications due to the abnormal shape of the red blood cells, which can lead to vascular occlusions and are more prone to bleeding. In particular, sickle cell patients often have fragile blood vessels in the eye, making them susceptible to bleeding events like hyphema, especially following trauma or in the context of increased intraocular pressure.

In contrast, other conditions listed, such as asthma, chronic migraines, and hypertension, do not have a direct association with hyphema. While hypertension can lead to vascular damage over time, it is not a primary risk factor for hyphema compared to the specific pathophysiological mechanisms present in sickle cell anemia. Thus, the condition that is most commonly linked with hyphema is indeed sickle cell anemia.