Which condition involves chronic inflammation of the conjunctiva, often due to contact lens wear?

Giant papillary conjunctivitis (GPC) is characterized by chronic inflammation of the conjunctiva, and it is frequently associated with the wear of contact lenses, particularly those that are rigid or extended wear. In GPC, the constant presence of a foreign object, such as a contact lens, can lead to an immune response resulting in the formation of large papillae on the inner eyelid. Symptoms can include itching, redness, secretion, and the feeling of a foreign body in the eye. This condition arises from mechanical irritation and an allergic response to materials in the contact lenses or their solutions.

In contrast, atopic conjunctivitis is associated with systemic allergic conditions and typically presents with more widespread skin involvement or a history of atopy rather than being specifically linked to contact lens use. Allergic conjunctivitis is related to seasonal or perennial allergens and is characterized by acute, transient symptoms rather than the chronic inflammation seen in GPC. Vernal keratoconjunctivitis is a more severe form of conjunctivitis with a different etiology, often impacting younger males, and involves corneal involvement and more extensive ocular symptoms.

GPC is particularly notable for its clear connection to contact lens wear, highlighting its relevance for individuals who use them regularly, making it