What is the significant disadvantage of using radioactive isotope plaques in treatment?

The significant disadvantage of using radioactive isotope plaques in treatment is that they can deliver high doses of radiation, which can affect nearby healthy tissue. This is particularly critical in delicate areas such as the eye, where the precise targeting of the tumor is essential to minimize damage to adjacent healthy structures. The concentrated radiation aimed at the tumor can inadvertently expose surrounding tissues, leading to potential complications and adverse effects.

This aspect is a central concern in treatment planning since the objective is not only to eradicate the tumor but also to preserve as much healthy tissue as possible to maintain function and quality of life. The balance between effectively targeting the tumor while protecting healthy tissue is a significant consideration in any treatment involving radioactive sources, making the radiation exposure a vital factor to monitor and manage during such interventions.