What is the recommended treatment for acute skin lesions associated with HZO?

The recommended treatment for acute skin lesions associated with herpes zoster ophthalmicus (HZO) involves emergency referral for systemic anti-viral treatment. This condition arises when the varicella-zoster virus reactivates, leading to painful skin lesions along the ophthalmic branch of the trigeminal nerve, along with potential complications like vision loss.

Timely administration of antiviral medications, such as acyclovir, is crucial because it can significantly reduce the severity of the disease, shorten the duration of the symptoms, and help prevent complications. This treatment is most effective when initiated within 72 hours of symptom onset.

Observation alone would not adequately address the risk of complications or the severity of the lesions. Over-the-counter (OTC) topical ointments do not possess antiviral properties that would affect the underlying viral infection and would be insufficient for treating acute lesions. Home remedies similarly lack proven efficacy in managing HZO and could delay appropriate medical intervention. Therefore, the priority is to ensure that systemic antiviral therapy is initiated promptly to manage the condition effectively.