What is the primary cause of hypopyon in the eye?

The primary cause of hypopyon in the eye is indeed related to the release of toxins from pathogens. Hypopyon is the accumulation of white blood cells in the anterior chamber of the eye, often as a result of an inflammatory response to infection. When pathogens such as bacteria, viruses, or fungi invade the eye, they can induce an inflammatory response characterized by the release of cytokines and other inflammatory mediators.

These substances can attract leukocytes to the site of infection, leading to their pooling in the anterior chamber. The presence of toxins produced by these pathogens can also further irritate the ocular tissues, exacerbating inflammation and contributing to the formation of hypopyon.

Infections that can lead to hypopyon include bacterial keratitis, endophthalmitis, and other severe ocular infections. This underscores the importance of identifying and treating the underlying infectious cause to manage the condition effectively.