How quickly can retinal degeneration occur after retinal detachment?

Retinal degeneration can occur relatively quickly following retinal detachment due to the loss of oxygen and nutrients that the retina normally receives from the underlying choroidal blood supply. When the retina becomes detached, it can begin to undergo irreversible changes within approximately 12 hours. This timeframe is critical because, if the retinal detachment is not promptly addressed surgically, the viability of the retina is compromised, leading to permanent vision loss.

Understanding the timeline of retinal degeneration emphasizes the urgency of medical intervention in cases of retinal detachment. Immediate surgical repair is essential within this time frame to preserve retinal function and prevent degeneration. Hence, the assertion that retinal degeneration can occur approximately 12 hours after retinal detachment aligns with clinical observations regarding the critical window for intervention.