How is the treatment protocol adjusted for patients with retinal tumors that have recurred after chemotherapy?

In the management of retinal tumors that have recurred after chemotherapy, cryotherapy can be prioritized as an important treatment option. This method utilizes extreme cold to destroy abnormal tissues, making it particularly useful for localized tumors or those that have not disseminated extensively. Cryotherapy can effectively target and shrink the tumor while preserving surrounding healthy retinal tissue, which is crucial for maintaining vision.

Additionally, the decision to use cryotherapy depends on various factors, including the tumor size, location, and the patient’s overall health status. It can be part of a multimodal approach that may include other therapeutic strategies like radiation or additional systemic therapies, depending on the specific characteristics of the recurrence.

Other treatment options, such as surgical excision and enucleation, may also be considered; however, these are typically more invasive and reserved for specific clinical scenarios. Radioactive isotope plaques are valuable but are not used as the exclusive option; they may be combined with other methods based on the tumor's attributes and the patient's condition. Prioritizing cryotherapy reflects a targeted approach aimed at maximizing the ability to control the tumor while preserving the patient's vision whenever possible.